Researchers work out the best way to flip dangerous reminiscences into good ones (in mice)

Researchers figure out how to turn bad memories into good ones (in mice)

We have all obtained reminiscences we want we might view much less negatively. Some are trivial, like that drunken show on the workplace celebration; some are critical and create real psychological challenges. Up to now, researchers have found out tips on how to create false ones, or take away them solely. Now — in mice a minimum of — scientists have transformed a nasty reminiscence into a superb one. The researches established good and dangerous reminiscences within the mice (with meals rewards, or mild shocks) and recorded the elements of the mind that handled the situation (hippocampus) of these occasions, and the emotional recording half (amygdala). To modify the reminiscences, when the mice returned to the situation the place they acquired the shock or meals, they triggered the situation reminiscence of the opposite occasion. The mice then displayed behaviours in step with the other reminiscence (shortly shifting from, or remaining calm within the present location). Whereas the work provides us a brand new perception into the mechanics of reminiscence, the method is just too complicated and invasive for there to be any hope of it getting used for remedy of apparent circumstances like PTSD. It might nevertheless result in additional validation of different therapies (like CBT) that work on comparable rules.

[Image credit: rduffy/Flickr]

By way of: Wired

Supply: Nature

Tags: reminiscences, mice, analysis

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