Now you can pull up your whole genome for beneath $1,000 in your smartphone
Veritas Genetics was one of many first corporations to sequence the whole human genome for beneath $1,000 in 2015. It’s now taken that know-how a step additional by delivering the outcomes of your whole genome in an app.
To place in context simply how radical that is, contemplate the primary try at entire human genome sequencing required $three.7 billion to supply in 2001. It wasn’t till 2007 when the primary commercially out there human genome sequencing got here onto the scene for a fraction of the price at $350,000.
The promise of entire human genome sequencing for beneath $1,000 was considerably of a catchphrase within the scientific group. Most shopper DNA corporations nonetheless solely offer you particular units of what’s in your DNA utilizing gene panels. You will get about 60 check outcomes from gene panels utilizing 23andMe, for instance.
However for $999 Veritas says its myGenome product will ship the entire shebang to your smartphone. The price consists of check outcomes and the good thing about genetic counseling that will help you decipher what these outcomes imply on your well being.
So somebody with a genetic predisposition for breast most cancers or Parkinsons will get a heads up and knowledge on attainable programs of motion. For example, Angelina Jolie came upon she carried the identical breast most cancers gene BRCA-1 as her mom did and opted for a double mastectomy earlier than the illness had an opportunity to develop.
Harvard genetics pioneer George Church co-based the corporate and first made entire genome sequencing out there to about 5,000 members within the Private Genome Venture (PGP) at Harvard Medical Faculty final yr.
Church believes the worth level and quick access will make entire genome sequencing the brand new normal. “Now that the entire genome is that this accessible, it is going to substitute all genetic checks … as a result of it is all genetic checks, and far, rather more,” Church stated.
Which may trigger hassle for some corporations hoping to money in on the progress we’ve made. Genetics suppliers have run into hassle with the federal government for offering check outcomes coping with well being circumstances up to now and one of many largest, 23andMe, needed to pull again and work on approval from the FDA for a few years earlier than being allowed to offer check outcomes for sure well being circumstances.
Veritas runs its exams in a CLIA-licensed lab and requires an order out of your physician first earlier than sequencing your genome so it might be okay right here, however issues might nonetheless go fallacious.
We aren’t capable of modify human genes simply but (not legally in the USA, at the least) however you’ll be able to see the place that is going. The decrease value and skill to entry the outcomes of your personal DNA might result in a higher demand from the general public and break down the legal guidelines stopping genetic engineering as drugs.
Whereas some may see that because the set off resulting in some dystopian “Gattaca” state of affairs, I’m excited to see the place any such know-how leads us, the lives it might probably save and even enhance.